DR1 抗体
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- 抗原 See all DR1 抗体
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DR1 protein
- 亚型
- IgG
- Top Product
- Discover our top product DR1 Primary Antibody
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anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) antibody
DR1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) antibodyDR1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) antibodyDR1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 1-176) antibodyDR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) antibodyDR1 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (N-Term) antibodyDR1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 小鸡, 斑马鱼, 兔, 马, 豚鼠, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 63-112) antibodyDR1 适用: 人, 小鼠, 大鼠, 犬, Pig, Cow, 小鸡, 斑马鱼, 兔, 马, 非洲爪蟾, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 2-170) antibodyDR1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (AA 83-112) antibodyDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37581 unconjugated
anti-TATA-Binding Protein-Associated Phosphoprotein (DR1) (N-Term) antibodyDR1 适用: 人, 小鼠, 大鼠, 犬, Cow, 斑马鱼, 兔, 马, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))
- 别名
- DR1 Protein (DR1 产品)
- 背景
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Synonyms: Dr1 protein; NC2; Negative cofactor 2 beta; Down regulator of transcription 1; Down regulator of transcription 1 TBP binding; Down-regulator of transcription 1; DR 1; Dr1; NC 2; NC2 beta; NC2-beta; NC2B_HUMAN; Negative co factor 2; Negative cofactor 2; Negative cofactor 2-beta; Protein Dr1; TATA binding protein associated phosphoprotein; TATA-binding protein-associated phosphoprotein.
Background: DR1, also known as NC2 (negative cofactor 2 subunit ), is a TFIID (TATA box-binding protein)-associated protein. DR1 localizes to the nucleus and contains an N-terminal histone fold motif, a TFIID-binding domain and an alanine and glutamine rich region. Via its histone fold motif, DR1 forms a heterodimer with NC2å (DRAP1) to comprise the conserved eukaryotic complex, NC2 (negative cofactor 2). The NC2 complex can both positively and negatively regulate transcription by RNA Pol II. More specifically, NC2 acts as a repressor of TATA-dependent transcription and acts as an activator for DPE-dependent transcription. NC2 represses RNA Pol II transcription by binding to TFIID and inhibiting association of the transcription factors TFIIA and TFIIB. NC2 activity is regulated by phosphorylation. Both subunits, NC2å and DR1, are phosphorylated in vivo.
- 基因ID
- 10589
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