OLIG1 抗体 (AA 121-220)
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- 抗原 See all OLIG1 抗体
- OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))
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抗原表位
- AA 121-220
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OLIG1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Dog,Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human OLIG1
- 亚型
- IgG
- Top Product
- Discover our top product OLIG1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- OLIG1 (Oligodendrocyte Transcription Factor 1 (OLIG1))
- 别名
- OLIG1 (OLIG1 产品)
- 别名
- OLIG1 antibody, BHLHB6 antibody, BHLHE21 antibody, AI836478 antibody, AW494459 antibody, Bhlhb6 antibody, Olg-1 antibody, Oligo1 antibody, bHLHe21 antibody, Olg1 antibody, oligodendrocyte transcription factor 1 antibody, OLIG1 antibody, Olig1 antibody
- 背景
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Synonyms: Oligo 1, Oligo1, Oligodendrocyte lineage transcription factor 1, Oligodendrocyte specic bHLH transcription factor 1, Oligodendrocyte transcription factor 1. Basic domain helix loop helix protein class B 6, Basic domain helix loop helix protein class B6, BHLH B6, BHLHB 6, BHLHB6, bHLHe21, Class B basic helix-loop-helix protein 6, Class E basic helix-loop-helix protein 21, Olig 1, Olig1, OLIG1_HUMAN.
Background: The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
- 基因ID
- 116448
- UniProt
- Q8TAK6
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