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FBXO15 抗体 (AA 101-200)

FBXO15 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386824
发货至: 中国
  • 抗原 See all FBXO15 抗体
    FBXO15 (F-Box Protein 15 (FBXO15))
    抗原表位
    • 14
    • 9
    • 8
    • 7
    • 5
    • 1
    • 1
    AA 101-200
    适用
    • 24
    • 15
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 38
    克隆类型
    • 38
    多克隆
    标记
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO15 antibody is un-conjugated
    应用范围
    • 33
    • 18
    • 14
    • 12
    • 12
    • 5
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Fbx15
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Chang, Hung, Zhang, Hsieh, Hsu, Ding: "A Novel Signature of CCNF-Associated E3 Ligases Collaborate and Counter Each Other in Breast Cancer." in: Cancers, Vol. 13, Issue 12, (2021) (PubMed).

  • 抗原
    FBXO15 (F-Box Protein 15 (FBXO15))
    别名
    Fbx15 (FBXO15 产品)
    别名
    fbx15 antibody, FBX15 antibody, AU019763 antibody, Fbx15 antibody, ecat3 antibody, F-box protein 15 antibody, zgc:161973 antibody, FBXO15 antibody, zgc:161973 antibody, fbxo15 antibody, Fbxo15 antibody
    背景

    Synonyms: F box protein 15, F-box only protein 15, F-box protein 15, Fbxo15, MGC39671, FBX15_HUMAN.

    Background: FBXO15, also known as FBX15, is a 434 amino acid protein that contains one C-terminal F-box domain and belongs to the F-box family of proteins. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-a and b-catenin, for degradation by the proteasome after ubiquitination. Via its F-box domain, FBXO15 can directly interact with Skp1 p19 and CUL-1. In addition, FBXO15 is a target of the transcription factor Oct-3/4, however, it does not appear to be essential for early development and fertility.

    基因ID
    201456
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