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RTN4IP1 抗体 (AA 111-210)

RTN4IP1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386808
发货至: 中国
  • 抗原 See all RTN4IP1 抗体
    RTN4IP1 (Reticulon 4 Interacting Protein 1 (RTN4IP1))
    抗原表位
    • 14
    • 8
    • 8
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 111-210
    适用
    • 34
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 44
    • 4
    克隆类型
    • 46
    • 2
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RTN4IP1 antibody is un-conjugated
    应用范围
    • 36
    • 19
    • 17
    • 15
    • 12
    • 12
    • 6
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NIMP/RTN4IP1
    亚型
    IgG
    Top Product
    Discover our top product RTN4IP1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    RTN4IP1 (Reticulon 4 Interacting Protein 1 (RTN4IP1))
    别名
    NIMP (RTN4IP1 产品)
    别名
    RTN4IP1 antibody, NIMP antibody, D10Ertd690e antibody, RGD1563384 antibody, reticulon 4 interacting protein 1 antibody, RTN4IP1 antibody, Rtn4ip1 antibody
    背景

    Synonyms: mitochondrial, NIMP, NOGO interacting mitochondrial protein, NOGO-interacting mitochondrial protein, Reticulon 4 interacting protein 1, Reticulon 4 interacting protein 1, mitochondrial, Reticulon-4-interacting protein 1, RT4I1_HUMAN, Rtn4ip1, NIMP/RTN4IP1.

    Background: Appears to be a potent inhibitor of regeneration following spinal cord injury.Nogo is an oligodendrocyte-specific member of the Reticulon family and is a component of CNS white matter that inhibits axon outgrowth, induces collapse of growth cones of chick dorsal root ganglion cells, and inhibits the spreading of 3T3 fibroblasts. Nogo is expressed by oligodendrocytes but not by Schwann cells, and associates primarily with the endoplasmic reticulum. Nogo exists in three different splice forms, Nogo-A, -B and -C. NIMP (NOGO-interacting mitochondrial protein), also known as RTN4IP1 (Reticulon-4-interacting protein 1), is a 396 amino acid mitochondrial protein that contains a C-terminal oxidoreductaselike domain and numerous sites for phosphorylation. NIMP is expressed in mitochondrial-rich tissue such as kidney, heart, skeletal muscle and specific regions within the nervous system. Through interaction with Nogo, it is likely that NIMP plays a role in Nogo-induced inhibition of neurite growth. There are three isoforms of NIMP that are produced as a result of alternative splicing events.

    基因ID
    84816
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