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ANK2 抗体 (AA 1901-2100)

ANK2 适用: 小鼠 IHC (p), ELISA, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386782
发货至: 中国
  • 抗原 See all ANK2 抗体
    ANK2 (Ankyrin 2, Neuronal (ANK2))
    抗原表位
    AA 1901-2100
    适用
    • 23
    • 12
    • 12
    • 2
    小鼠
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ANK2 antibody is un-conjugated
    应用范围
    • 25
    • 25
    • 12
    • 10
    • 10
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Ankyrin B
    亚型
    IgG
    Top Product
    Discover our top product ANK2 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    ANK2 (Ankyrin 2, Neuronal (ANK2))
    别名
    Ankyrin B (ANK2 产品)
    别名
    ANK-2 antibody, LQT4 antibody, brank-2 antibody, AI835472 antibody, AW491075 antibody, Ank-2 antibody, Ank3 antibody, CHANK2 antibody, ANK2 antibody, ank2 antibody, zgc:101738 antibody, ANKB antibody, ankyrin 2 antibody, ankyrin 2, brain antibody, ankyrin-2 antibody, ankyrin 2b, neuronal antibody, ANK2 antibody, Ank2 antibody, LOC539238 antibody, ank2b antibody, LOC100465763 antibody
    背景

    Synonyms: ANK-2, Ank2, ANK2_HUMAN, Ankyrin 2, Ankyrin 2 brain, Ankyrin B, Ankyrin nonerythroid, ANKYRIN, NEURONAL, Ankyrin-2, Ankyrin-B, Brain ankyrin, Non-erythroid ankyrin

    Background: Members of the Ankyrin family of proteins mediate the attachment of integral membrane proteins to the cytoskeleton. ANK1, ANK2 and ANK3 genes encode for the proteins in this family, Ankyrin-1 (also designated Ankyrin R), Ankyrin B and Ankyrin G, respectively. The proteins are structured similarly each composed of an N-terminal domain with multiple ankyrin repeats, a highly conserved central spectrin binding domain, and C-terminal regulatory domains which are susceptible to the most variance. Both Ankyrin B and Ankyrin G are essential for normal neuronal functions. Ankyrin B, or brain Ankyrin is predominantly expressed in the plasma membrane of neurons as well as glial cells throughout the brain. Two transcripts have been described with alternative splicing resulting in additional isoforms. The Ankyrin B protein associates with the spectrin-actin network, mediates axon fasciculation, and stabilizes axon bundles. Ankyrin B is required for coordinated assembly of Na/Ca exchanger, Na/K ATPase, and inositol trisphosphate (InsP(3)) receptor at transverse-tubule/sarcoplasmic reticulum sites in cardiomyocytes.

    基因ID
    287
    途径
    Cell-Cell Junction Organization
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