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mGluR1 + mGluR5 抗体 (AA 501-600)

mGluR1/5 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386658
发货至: 中国
  • 抗原 See all mGluR1 + mGluR5 (mGluR1/5) products
    mGluR1 + mGluR5 (mGluR1/5) (Glutamate Receptor, Metabotropic 5/1 (mGluR1/5))
    抗原表位
    • 16
    • 5
    • 3
    • 2
    AA 501-600
    适用
    • 23
    • 22
    • 21
    • 2
    小鼠
    宿主
    • 18
    • 8
    克隆类型
    • 18
    • 8
    多克隆
    标记
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This mGluR1 + mGluR5 antibody is un-conjugated
    应用范围
    • 26
    • 14
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MGLUR1 + MGLUR5
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    mGluR1 + mGluR5 (mGluR1/5) (Glutamate Receptor, Metabotropic 5/1 (mGluR1/5))
    别名
    MGLUR1 + MGLUR5 (mGluR1/5 产品)
    背景

    Synonyms: MGLUR1+MGLUR5, GPRC1A, GPRC1E, GRM1, GRM1A, GRM5, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, mGlu1, mGlu5, MGLUR1, MGLUR1A, MGLUR5, MGLUR5B, GRM1_HUMAN, GRM5_HUMAN.

    Background: Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include Metabotropic Glutamate Receptor 5 and Metabotropic Glutamate Receptor 1a. The Group-II receptors in include mGluR2 and mGluR3.

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