SLC5A3 抗体 (AA 251-350)
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- 抗原 See all SLC5A3 抗体
- SLC5A3 (Solute Carrier Family 5 Member 3 (SLC5A3))
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抗原表位
- AA 251-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC5A3 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SLC5A3/SMIT
- 亚型
- IgG
- Top Product
- Discover our top product SLC5A3 Primary Antibody
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anti-Solute Carrier Family 5 Member 3 (SLC5A3) (AA 533-641) antibody
SLC5A3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3A6 unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) antibodySLC5A3 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) (Internal Region) antibodySLC5A3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) (Internal Region) antibodySLC5A3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) (AA 221-270) antibodySLC5A3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) (C-Term) antibodySLC5A3 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) antibodySLC5A3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 5 Member 3 (SLC5A3) (AA 533-641) antibodySLC5A3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- SLC5A3 (Solute Carrier Family 5 Member 3 (SLC5A3))
- 别名
- SLC5A3/SMIT (SLC5A3 产品)
- 别名
- AA623876 antibody, BF642829 antibody, Smit1 antibody, SMIT antibody, SMIT1 antibody, SMIT2 antibody, Smit antibody, solute carrier family 5 (inositol transporters), member 3 antibody, solute carrier family 5 member 3 antibody, Slc5a3 antibody, SLC5A3 antibody
- 背景
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Synonyms: Na+/myo inositol cotransporter, Na+/myo-inositol cotransporter, SC5A3_HUMAN, SLC5A3, SMIT, SMIT2, sodium/myo inositol cotransporter 1, Sodium/myo inositol cotransporter, Sodium/myo-inositol cotransporter, solute carrier family 5 inositol transporters, member 3, Solute carrier family 5 member 3.
Background: Myo-inositol is involved in many important aspects of cellular regulation including membrane structure, signal transduction and osmoregulation. It is taken up into cells by the sodium/myo-inositol cotransporter (SMIT). SMIT activity maintains intracellular concentrations of myo-inositol, it is upregulated in response to hypertonic stress. The human SMIT protein is encoded by the SLC5A3 gene, which maps to chromosome 21q22.12. It is expressed in many human tissues, such as brain, kidney and placenta. Specifically, SMIT is abundantly expressed throughout the whole brain and spinal cord in fetal rat, but is downregulated in adult rat brain with the exception of the choroid plexus, where SMIT expression remains high. In kidney, SMIT localizes to the baso-lateral membranes of the thick ascending limb of Henle (TAL) and the inner medullary collecting duct (IMCD). Impaired SMIT activity is implicated in the pathogenesis of diabetes and Down syndrome.
- 途径
- Inositol Metabolic Process
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