NME4 抗体 (AA 21-120)
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- 抗原 See all NME4 抗体
- NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))
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抗原表位
- AA 21-120
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NME4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NME4/nm23-H4
- 亚型
- IgG
- Top Product
- Discover our top product NME4 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))
- 别名
- NME4/nm23-H4 (NME4 产品)
- 别名
- NDPK-D antibody, NM23H4 antibody, nm23-H4 antibody, 2610027N22Rik antibody, 2810024O08Rik antibody, 5730493H09Rik antibody, NM23-M4 antibody, Nm23M4 antibody, NME/NM23 nucleoside diphosphate kinase 4 antibody, NME4 antibody, Nme4 antibody
- 背景
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Synonyms: mitochondrial, NDK, NDKM_HUMAN, NDP kinase, NDP kinase, mitochondrial, NDPKD, nm23 H4, nm23-H4, NM23D, Nm23M4, NME4, Non metastatic cells 4 protein expressed in, Nucleoside diphosphate kinase D, Nucleoside diphosphate kinase, mitochondrial.
Background: The nm23 gene (Metastasis inhibition factor nm23), a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. Based on sequence analysis, nm23, also designated nucleoside diphosphate kinase A (NDK A) or Tumor metastatic process-associated protein, appears to be highly related to nucleotide diphosphate kinases (NDP). NDP kinases A and B are identical to two isotypes of human nm23 homologs, nm23-H1 and nm23-H2, respectively. nm23-H2 is also identical in sequence to PuF, a transcription factor that binds to nuclease-hypersensitive elements at positions 142 to 115 of the human c-Myc promoter. nm23-H3 and nm23-H4 are important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis. nm23-H4 localizes to the mitochondrial intermembrane space and is widely expressed, with higher levels detected in prostate, heart, liver, small intestine, and skeletal muscle tissues. Low amounts of nm23-H4 are observed in the brain and in blood leukocytes.
- 途径
- Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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