MAP3K4 抗体 (AA 1351-1450)
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- 抗原 See all MAP3K4 抗体
- MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
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抗原表位
- AA 1351-1450
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAP3K4 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MAP3K4/MEK kinase-4
- 亚型
- IgG
- Top Product
- Discover our top product MAP3K4 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- MAP3K4 (Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4))
- 别名
- MAP3K4/MEK kinase-4 (MAP3K4 产品)
- 别名
- MAPKKK4 antibody, MEKK4 antibody, MTK1 antibody, PRO0412 antibody, D17Rp17 antibody, D17Rp17e antibody, MEKK 4 antibody, Mek4b antibody, Mekk4 antibody, RP17 antibody, Rp17a antibody, Tas antibody, mKIAA0213 antibody, mitogen activated protein kinase kinase kinase 4 antibody, mitogen-activated protein kinase kinase kinase 4 antibody, Map3k4 antibody, MAP3K4 antibody
- 背景
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Synonyms: FLJ42439, KIAA0213, M3K4_HUMAN, MAP three kinase 1, MAP3K4, MAPK/ERK kinase kinase 4, MAPKKK4 antibodyMEK kinase 4, MEKK 4, MEKK4, Mitogen-activated protein kinase kinase kinase 4, MTK1, PRO0412, RP3-473J16.4
Background: Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and p38. These activated MEKs in turn phosphorylate and activate the MAP kinases. The MEK kinases include Raf-1, Raf-B, Mos, MEK kinase-1, MEK kinase-2, MEK kinase-3, MEK kinase-4, ASK 1 (MEK kinase-5) and MAP3K6 (MEK kinase-6). MEK kinase-1 has been shown to phosphorylate MEK-1 via Raf-independent pathway. Evidence suggests that MEK-3 is preferentially activated by MEK kinase-3 and that MEK-4 is activated by both MEK kinase-2 and MEK kinase-3. MEK kinase-4 has been shown to specifically activate the JNK path-way. ASK1 activates both MEK-4 and MEK-3/MEK-6 pathways.
- 途径
- MAPK Pathway
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