NAB2 抗体 (AA 221-320)
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- 抗原 See all NAB2 抗体
- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
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抗原表位
- AA 221-320
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NAB2
- 亚型
- IgG
- Top Product
- Discover our top product NAB2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
- 别名
- NAB2/MADER (NAB2 产品)
- 别名
- mader antibody, AI451907 antibody, MADER antibody, NGFI-A binding protein 2 (EGR1 binding protein 2) antibody, Ngfi-A binding protein 2 antibody, NGFI-A binding protein 2 antibody, nab2 antibody, Nab2 antibody, NAB2 antibody
- 背景
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Synonyms: EGR 1 binding protein 2, EGR-1-binding protein 2, EGR1 binding protein 2, MADER, Melanoma associated delayed early response protein, Melanoma-associated delayed early response protein, MGC75085, Nab 2, nab2, NAB2_HUMAN, NGFI A binding protein 2 EGR1 binding protein 2, NGFI A binding protein 2, NGFI-A-binding protein 2, Protein MADER.
Background: Transcriptional control is in part regulated by interactions between DNA-bound transcription factors, such as Egr-1/NGFI-A, and coregulatory proteins, such as NAB (for NGFI-A-binding proteins). The evolutionarily conserved NAB proteins, NAB1 and NAB2 are corepressors of EGF-1/NGFI-A. Both NAB1 and NAB2 contain an amino terminal NAB conserved domain 1 (NCB1), which is required for binding NGFI-A, and a carboxy terminal NCD2 domain, which is responsible for the repressor function of NAB proteins. NAB2 is principally localized in the nucleus and may play a role in the downregulation of NGFI-A activity as well as in controlling fundamental processes such as cell division, differentiation and apoptosis. NAB2 localizes to chromosome 12q13.3-14.1, a region that is rearranged in several solid tumors, lipomas, and liposarcomas.
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