FICD 抗体 (AA 161-250)
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- 抗原 See all FICD 抗体
- FICD (FIC Domain Containing (FICD))
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抗原表位
- AA 161-250
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FICD antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HYPE
- 亚型
- IgG
- Top Product
- Discover our top product FICD Primary Antibody
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anti-FIC Domain Containing (FICD) (AA 63-185) antibody
FICD 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (AA 1-449) antibodyFICD 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-FIC Domain Containing (FICD) (AA 1-458) antibodyFICD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (AA 351-400) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, Pig, 兔, Bat, 猴, Drosophila melanogaster, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, Pig, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FIC Domain Containing (FICD) (C-Term) antibodyFICD 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- FICD (FIC Domain Containing (FICD))
- 别名
- HYPE/HIP13 (FICD 产品)
- 别名
- HIP13 antibody, HYPE antibody, UNQ3041 antibody, D5Ertd40e antibody, Hype antibody, FIC domain containing antibody, FICD antibody, Ficd antibody
- 背景
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Synonyms: Adenosine monophosphate-protein transferase FICD, AMPylator FICD, FIC domain containing, FIC domain containing protein, FIC domain-containing protein, Fic S phase protein cell division homolog, ficd, FICD_HUMAN, HIP-13, HIP13, Huntingtin interacting protein 13, Huntingtin interacting protein E, Huntingtin interactor protein E, Huntingtin yeast partner E, Huntingtin-interacting protein 13, Huntingtin-interacting protein E.
Background: Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein. HYPE is thought to interact with Huntingtin, a protein which induces neurodegeneration when mutated. HYPE also contains two tetratricopeptide repeats (TPR), which may be involved in protein-protein interaction. The gene that encodes HYPE is located on chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
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