DIS3L2 抗体
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- 抗原 See all DIS3L2 抗体
- DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DIS3L2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DIS3L2
- 亚型
- IgG
- Top Product
- Discover our top product DIS3L2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
- 别名
- DIS3L2 (DIS3L2 产品)
- 别名
- RGD1560168 antibody, DIS3L2 antibody, DKFZp469O0522 antibody, FAM6A antibody, PRLMNS antibody, hDIS3L2 antibody, 4930429A22Rik antibody, 8030493P09Rik antibody, DIS3-like 3'-5' exoribonuclease 2 antibody, DIS3 like 3'-5' exoribonuclease 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, DIS3L2 antibody, LOC100344728 antibody
- 背景
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Synonyms: DIS3 L2, DIS3 mitotic control homolog S. cerevisiae like 2, DIS3 mitotic control homolog like 2, FLJ36974, MGC42174, DI3L2_HUMAN.
Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3? region. DIS3L2 (DIS3-like exonuclease 2) is an 885 amino acid protein that is thought to function as an exonuclease and may be required for the 3? processing of pre-mRNA into mature mRNA. Defects or chromosomal translocations involving the gene encoding DIS3L2 may be associated with Marfanoid habitus, a genetic disorder characterized by abnormalities in the skeleton, eyes and cardiovascular system. DIS3L2 is expressed as five isoforms due to alternative splicing events.
- 基因ID
- 129563
- 途径
- Stem Cell Maintenance
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