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RASSF5 抗体 (AA 321-418)

RASSF5 适用: 人 IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386228
发货至: 中国
  • 抗原 See all RASSF5 抗体
    RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
    抗原表位
    • 14
    • 3
    • 2
    • 2
    • 1
    AA 321-418
    适用
    • 28
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    • 7
    克隆类型
    • 24
    • 4
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASSF5 antibody is un-conjugated
    应用范围
    • 14
    • 12
    • 12
    • 6
    • 2
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RASSF5
    亚型
    IgG
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Yang, Kong, Jin, Hergovich, Püschel: "Rassf5 and Ndr kinases regulate neuronal polarity through Par3 phosphorylation in a novel pathway." in: Journal of cell science, Vol. 127, Issue Pt 16, pp. 3463-76, (2014) (PubMed).

  • 抗原
    RASSF5 (Ras Association (RalGDS/AF-6) Domain Family Member 5 (RASSF5))
    别名
    RASSF5 (RASSF5 产品)
    别名
    Maxp1 antibody, NORE1 antibody, NORE1A antibody, NORE1B antibody, RAPL antibody, RASSF3 antibody, 1300019G20Rik antibody, AU042887 antibody, Nore1 antibody, Nore1A antibody, Nore1B antibody, Rapl antibody, Ras association domain family member 5 antibody, Ras association (RalGDS/AF-6) domain family member 5 antibody, RASSF5 antibody, Rassf5 antibody
    背景

    Synonyms: RAPL, Maxp1, NORE1, NORE1A, NORE1B, RASSF3, Ras association domain-containing protein 5, New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RASSF5

    Background: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation. Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.

    基因ID
    83593
    UniProt
    Q8WWW0
    途径
    TCR Signaling
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