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FNTA 抗体

FNTA 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386076
发货至: 中国
  • 抗原 See all FNTA 抗体
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    适用
    • 54
    • 25
    • 19
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    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 52
    • 2
    克隆类型
    • 53
    • 1
    多克隆
    标记
    • 19
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    This FNTA antibody is un-conjugated
    应用范围
    • 47
    • 21
    • 12
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PGGT1A/FNTA
    亚型
    IgG
    Top Product
    Discover our top product FNTA Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    别名
    PGGT1A (FNTA 产品)
    别名
    ATFTA antibody, FARNESYLTRANSFERASE A antibody, FARNESYLTRANSFERASE SUBUNIT A antibody, PFT/PGGT-IALPHA antibody, PLP antibody, PLURIPETALA antibody, farnesyltransferase A antibody, FPTA antibody, PGGT1A antibody, PTAR2 antibody, PFAS antibody, FTA antibody, farnesyltransferase A antibody, farnesyltransferase, CAAX box, alpha antibody, FTA antibody, FNTA antibody, Fnta antibody
    背景

    Synonyms: CAAX farnesyltransferase alpha subunit, Farnesyl protein transferase alpha subunit, Farnesyltransferase CAAX box alpha, Farnesyltransferase, CAAX box, alpha, FPTA, FTase alpha, GGTase I alpha, PGGT1A, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein prenyltransferase alpha subunit repeat containing 2, PTAR2, Ras proteins prenyltransferase alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl geranyltransferase alpha subunit, FNTA_HUMAN.

    Background: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

    基因ID
    2339
    途径
    Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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