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SRCAP 抗体 (AA 665-780)

SRCAP 适用: 人 ELISA, IHC (p), IF (p), IHC (fro), ICC, IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386056
发货至: 中国
  • 抗原 See all SRCAP 抗体
    SRCAP (Snf2-Related CREBBP Activator Protein (SRCAP))
    抗原表位
    • 1
    • 1
    AA 665-780
    适用
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This SRCAP antibody is un-conjugated
    应用范围
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SRCAP
    亚型
    IgG
    Top Product
    Discover our top product SRCAP Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SRCAP (Snf2-Related CREBBP Activator Protein (SRCAP))
    别名
    SRCAP (SRCAP 产品)
    别名
    DOMO1 antibody, EAF1 antibody, FLHS antibody, SWR1 antibody, B930091H02Rik antibody, D030022P06Rik antibody, F630004O05Rik antibody, RGD1565642 antibody, Snf2 related CREBBP activator protein antibody, Snf2-related CREBBP activator protein antibody, SRCAP antibody, Srcap antibody
    背景

    Synonyms: DOMO1, EAF1, Helicase SRCAP, Snf2 related CBP activator protein, SWR1, SRCAP_HUMAN.

    Background: SRCAP (Snf2-related CREBBP activator protein), also known as EAF1, SWR1, or DOMO1, is a 3,230 amino acid protein that belongs to a family of helicases and contains one HSA domain, one helicase C-terminal domain, one helicase ATP-binding domain and three A.T hook DNA-binding domains. Localized to the nucleus, SRCAP functions as a catalytic component of the SRCAP complex, a multi-protein structure that mediates the ATP-dependent exchange of histone dimers for nucleosomal histones, an event that regulates the transcription of select genes via chromatin remodeling. Additionally, the SRCAP complex acts as a coactivator for steroid receptor-mediated transcription, Notch-mediated transcription and CREB-mediated transcription. SRCAP is expressed as multiple alternatively spliced isoforms and is subject to DNA damage-dependent phosphorylation by ATM or ATR.

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