ALIX 抗体 (AA 301-380)
-
- 抗原 See all ALIX (PDCD6IP) 抗体
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
-
抗原表位
- AA 301-380
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ALIX antibody is un-conjugated
-
应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AIP1
- 亚型
- IgG
- Top Product
- Discover our top product PDCD6IP Primary Antibody
-
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-239) antibody
PDCD6IP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-180) antibodyPDCD6IP 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 174-383) antibodyPDCD6IP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-110) antibodyPDCD6IP 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C4 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 601-700) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人 WB, ELISA, FACS 宿主: 兔 Monoclonal 7E9 unconjugated Recombinant Antibody
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) antibodyPDCD6IP 适用: 人, 小鼠, 大鼠, 非洲爪蟾 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 3A9 unconjugated
anti-Programmed Cell Death 6 Interacting Protein (PDCD6IP) (AA 1-868) antibodyPDCD6IP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))
- 别名
- AIP1 (PDCD6IP 产品)
- 背景
-
Synonyms: Activin receptor interacting protein 1, Acvri1, Acvrinp1, ACVRIP1, AIP 1, Aip-1, ARIP1, Atrophin 1 interacting protein 1, Atrophin 1 interacting protein A, Atrophin-1-interacting protein 1, Atrophin-1-interacting protein A, MAGI-2, MAGI2, MAGI2_HUMAN, Membrane associated guanylate kinase 2, Membrane associated guanylate kinase inverted 2, Membrane associated guanylate kinase WW and PDZ domain containing 2, Membrane associated guanylate kinase WW and PDZ domain containing protein 2, Membrane-associated guanylate kinase, Membrane-associated guanylate kinase inverted 2, S SCAM, SSCAM, WW and PDZ domain-containing protein 2.
Background: AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumor suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), implicating a role for AIP1 fusion proteins in tumorigenesis.
- 途径
- p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
-
