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APBB3 抗体 (AA 401-486)

APBB3 适用: 大鼠, 小鼠 WB, IF (cc), IF (p), ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385994
发货至: 中国
  • 抗原 See all APBB3 抗体
    APBB3 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-486
    适用
    • 18
    • 16
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 26
    • 3
    克隆类型
    • 27
    • 1
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APBB3 antibody is un-conjugated
    应用范围
    • 29
    • 12
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Sheep
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human APBB3/FE65L2
    亚型
    IgG
    Top Product
    Discover our top product APBB3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    APBB3 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 3 (APBB3))
    别名
    APBB3/FE65L2 (APBB3 产品)
    别名
    Fe65l2 antibody, Rirl2 antibody, TR2S antibody, MGC142933 antibody, FE65L2 antibody, SRA antibody, amyloid beta (A4) precursor protein-binding, family B, member 3 antibody, steroid receptor RNA activator 1 antibody, amyloid beta precursor protein binding family B member 3 antibody, Apbb3 antibody, SRA1 antibody, APBB3 antibody, apbb3 antibody
    背景

    Synonyms: Amyloid beta A4 precursor protein binding family B member 3, Amyloid beta A4 precursor protein-binding family B member 3, amyloid beta precursor protein binding family B member 3, amyloid precursor interacting protein, Apbb3, APBB3_HUMAN, Fe65 like protein 2, FE65L2, Protein Fe65-like 2, SRA.

    Background: Fe65L2 is a 486 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the -Amyloid precursor protein, Fe65L2 is thought to modulate the internalization and, therefore, the accessibility and function of -Amyloid. Via its ability to control the intracellular accumulation of -Amyloid, Fe65L2 is thought to play a role in the pathogenesis of Alzheimer's disease. Fe65L2 exists as four alternatively spliced isoforms designated isoform I, isoform II, isoform III and isoform IV. Fe65L2 interacts with Amyloid-like protein and is encoded by a gene located on human chromosome 5, which contains 181 million base pairs and comprises nearly 6 % of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

    基因ID
    10307
    UniProt
    O95704
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