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MKRN2 抗体

MKRN2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385984
发货至: 中国
  • 抗原 See all MKRN2 抗体
    MKRN2 (Makorin Ring Finger Protein 2 (MKRN2))
    适用
    • 53
    • 22
    • 21
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 47
    • 6
    克隆类型
    • 49
    • 4
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MKRN2 antibody is un-conjugated
    应用范围
    • 48
    • 20
    • 12
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MKRN2/RNF62
    亚型
    IgG
    Top Product
    Discover our top product MKRN2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MKRN2 (Makorin Ring Finger Protein 2 (MKRN2))
    别名
    RNF62 (MKRN2 产品)
    别名
    MKRN2 antibody, RNF62 antibody, MGC131105 antibody, mkrn2 antibody, Makorin-2 antibody, hspc070 antibody, wu:fb99a04 antibody, 2610002L04Rik antibody, C81377 antibody, makorin ring finger protein 2 antibody, makorin ring finger protein 2 pseudogene antibody, makorin ring finger protein 2 L homeolog antibody, makorin-2 antibody, makorin, ring finger protein, 2 antibody, MKRN2 antibody, LOC100401355 antibody, mkrn2 antibody, mkrn2.L antibody, Mkrn2 antibody
    背景

    Synonyms: HSPC070_ Makorin 2, Makorin ring finger protein 2, Makorin2, Makorin-2 MKRN 2, RING finger protein 62, RNF 62, RNF62, MKRN2_HUMAN, Probable E3 ubiquitin-protein ligase makorin-2, RING finger protein 62.

    Background: The Makorins are a family of putative ribonucleoproteins containing two to four C3H zinc fingers that may confer RNA-binding. In addition, they contain a C3HC4 RING zinc finger that allows them to function as E3 ubiquitin ligases. Makorin-2, also known as RNF62, HSPC070 or MKRN2, is a widely expressed, evolutionarily conserved protein with four C3H-type zinc fingers (three at the N-terminus and one at the C-terminus), one RING-type zinc finger and a cysteine and histidine motif similar to that found in Makorin-1. In Xenopus, Makorin-2 functions, via PI 3-kinase/Akt signaling, as a negative regulator of neurogenesis. In humans, Makorin-2 is overexpressed in various cancer cell lines, suggesting a possible role of Makorin-2 in tumor progression. In addition, Makorin-2 is co-expressed with Raf-1 in the same tissues and cell lines.

    基因ID
    23609
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