MKRN2 抗体
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- 抗原 See all MKRN2 抗体
- MKRN2 (Makorin Ring Finger Protein 2 (MKRN2))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MKRN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MKRN2/RNF62
- 亚型
- IgG
- Top Product
- Discover our top product MKRN2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- MKRN2 (Makorin Ring Finger Protein 2 (MKRN2))
- 别名
- RNF62 (MKRN2 产品)
- 别名
- MKRN2 antibody, RNF62 antibody, MGC131105 antibody, mkrn2 antibody, Makorin-2 antibody, hspc070 antibody, wu:fb99a04 antibody, 2610002L04Rik antibody, C81377 antibody, makorin ring finger protein 2 antibody, makorin ring finger protein 2 pseudogene antibody, makorin ring finger protein 2 L homeolog antibody, makorin-2 antibody, makorin, ring finger protein, 2 antibody, MKRN2 antibody, LOC100401355 antibody, mkrn2 antibody, mkrn2.L antibody, Mkrn2 antibody
- 背景
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Synonyms: HSPC070_ Makorin 2, Makorin ring finger protein 2, Makorin2, Makorin-2 MKRN 2, RING finger protein 62, RNF 62, RNF62, MKRN2_HUMAN, Probable E3 ubiquitin-protein ligase makorin-2, RING finger protein 62.
Background: The Makorins are a family of putative ribonucleoproteins containing two to four C3H zinc fingers that may confer RNA-binding. In addition, they contain a C3HC4 RING zinc finger that allows them to function as E3 ubiquitin ligases. Makorin-2, also known as RNF62, HSPC070 or MKRN2, is a widely expressed, evolutionarily conserved protein with four C3H-type zinc fingers (three at the N-terminus and one at the C-terminus), one RING-type zinc finger and a cysteine and histidine motif similar to that found in Makorin-1. In Xenopus, Makorin-2 functions, via PI 3-kinase/Akt signaling, as a negative regulator of neurogenesis. In humans, Makorin-2 is overexpressed in various cancer cell lines, suggesting a possible role of Makorin-2 in tumor progression. In addition, Makorin-2 is co-expressed with Raf-1 in the same tissues and cell lines.
- 基因ID
- 23609
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