PJA2 抗体 (AA 420-470)
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- 抗原 See all PJA2 抗体
- PJA2 (Praja Ring Finger 2 (PJA2))
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抗原表位
- AA 420-470
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PJA2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PJA2/RNF131
- 亚型
- IgG
- Top Product
- Discover our top product PJA2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- PJA2 (Praja Ring Finger 2 (PJA2))
- 别名
- RNF131 (PJA2 产品)
- 别名
- PJA2 antibody, AI447901 antibody, AL022700 antibody, Neurodap1 antibody, mKIAA0438 antibody, RNF131 antibody, praja2 antibody, praja ring finger ubiquitin ligase 2 antibody, PJA2 antibody, Pja2 antibody
- 背景
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Synonyms: E3 ubiquitin protein ligase Praja2, E3 ubiquitin-protein ligase Praja-2, KIAA0438, Neurodap 1, Neurodap1, PJA 2, PJA2, PJA2_HUMAN, Praja 2, Praja 2 RING H2 mot containing, praja ring finger 2, Praja ring finger 2 E3 ubiquitin protein ligase, Praja2, RING finger protein 131, RNF 131, RNF131.
Background: PJA2, also known as E3 ubiquitin-protein ligase praja-2, RNF131 (ring finger protein 131) or Neurodap1, is a 708 amino acid protein that contains one ring-type zinc finger and exists as two alternatively spliced isoforms. Significantly conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PJA2 shares 52 % identity with PJA1, which is involved in protein ubiquitination in brain and may play a role in X-linked mental retardation. Encoded by a gene that maps to human chromosome 5q21.3, PJA2 localizes to both endoplasmic reticulum and Golgi apparatus membranes. Participating in E2-dependent, E3 ubiquitin-protein ligase activity, PJA2 binds to a variety of E2s and interacts with ubiquitin-conjugating enzymes, such as UBE2D2, in vitro.
- 基因ID
- 9867
- UniProt
- O43164
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