GPS1 抗体 (AA 324-370)
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- 抗原 See all GPS1 抗体
- GPS1 (G Protein Pathway Suppressor 1 (GPS1))
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抗原表位
- AA 324-370
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CSN1
- 亚型
- IgG
- Top Product
- Discover our top product GPS1 Primary Antibody
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anti-G Protein Pathway Suppressor 1 (GPS1) (AA 258-527) antibody
GPS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (C-Term) antibodyGPS1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) antibodyGPS1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (C-Term) antibodyVerified GPS1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 222-491) antibodyGPS1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 1-527) antibodyGPS1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) antibodyGPS1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (AA 390-491) antibodyGPS1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E8 unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (N-Term) antibodyGPS1 适用: 人, 小鼠, Cow, 小鸡, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-G Protein Pathway Suppressor 1 (GPS1) (N-Term) antibodyGPS1 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- GPS1 (G Protein Pathway Suppressor 1 (GPS1))
- 别名
- CSN1 (GPS1 产品)
- 背景
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Synonyms: CSN1, COPS1, COP9 signalosome complex subunit 1, SGN1, Signalosome subunit 1, G protein pathway suppressor 1, GPS-1, JAB1-containing signalosome subunit 1, Protein MFH, GPS1
Background: Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction.
- 基因ID
- 2873
- UniProt
- Q13098
- 途径
- Cell Division Cycle
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