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CTNND2 抗体 (AA 951-1050)

CTNND2 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385884
发货至: 中国
  • 抗原 See all CTNND2 抗体
    CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
    抗原表位
    • 14
    • 14
    • 10
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    AA 951-1050
    适用
    • 53
    • 21
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 48
    • 5
    克隆类型
    • 49
    • 4
    多克隆
    标记
    • 17
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTNND2 antibody is un-conjugated
    应用范围
    • 25
    • 24
    • 15
    • 12
    • 12
    • 8
    • 2
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human delta 2 Catenin
    亚型
    IgG
    Top Product
    Discover our top product CTNND2 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    CTNND2 (Catenin (Cadherin-Associated Protein), delta 2 (Neural Plakophilin-Related Arm-Repeat Protein (CTNND2))
    别名
    CTNND2/delta 2 Catenin (CTNND2 产品)
    别名
    CTNND2 antibody, Catnd2 antibody, Nprap antibody, neurojugin antibody, GT24 antibody, NPRAP antibody, ctnnd2 antibody, si:dkey-40c17.4 antibody, catenin delta 2 antibody, delta-catenin antibody, catenin delta-2 antibody, catenin (cadherin associated protein), delta 2 antibody, catenin (cadherin-associated protein), delta 2b antibody, CTNND2 antibody, BACOIKO001_27 antibody, LOC100070792 antibody, Ctnnd2 antibody, ctnnd2b antibody
    背景

    Synonyms: Catenin cadherin associated protein delta 2, Catenin delta 2, Catenin delta-2, CTND2_HUMAN, CTNND 2, CTNND2, Delta catenin, Delta-catenin, GT 24, GT24, Neural plakophilin related arm repeat protein, Neural plakophilin related armadillo repeat protein, Neural plakophilin-related ARM-repeat protein, Neurojungin, NPRAP

    Background: The Alpha-, Beta-, Gamma-, and Delta -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. Alpha-catenin interacts with E-cadherin associated protein and also associates with other members of the cadherin family, such as N-cadherin and P-cadherin. Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. Beta-catenin also complexes with the tumor suppressor protein APC. Gamma-catenin, also known as plakoglobin, is a protein that binds ?catenin and N-cadherin. Gamma-catenin interacts with presenilin 1 and is expressed in the brain. The gene encoding Gamma-catenin maps to human chromosome 5p15.2. A hemizygous loss of the gene encoding Gamma-catenin leads to the mental retardation associated with Cri-du-Chat syndrome. In addition, the transmembrane phosphatase PTPm associates with catenin/ cadherin complexes and may regulate complex signaling.

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