RENT1/UPF1 抗体 (AA 301-450)
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- 抗原 See all RENT1/UPF1 (UPF1) 抗体
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
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抗原表位
- AA 301-450
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RENT1/UPF1 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RENT1/hUPF1
- 亚型
- IgG
- Top Product
- Discover our top product UPF1 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
- 别名
- RENT1/hUPF1 (UPF1 产品)
- 背景
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Synonyms: ATP dependent helicase RENT1, ATP-dependent helicase RENT1, Delta helicase, HUPF 1, HUPF1, KIAA0221, Nonsense mRNA reducing factor 1, NORF 1, NORF1, pNORF 1, pNORF1, Regulator of nonsense transcripts 1, RENT 1, RENT1, RENT1_HUMAN, Smg 2, Smg 2 homolog nonsense mediated mRNA decay factor, UP Framesht 1, Up framesht mutation 1 homolog S. cerevisiae, Up framesht mutation 1 homolog, Up framesht suppressor 1 homolog, Up-framesht mutation 1 homolog S. cerevisiae, Up-framesht suppressor 1 homolog, UPF 1, UPF 1 regulator of nonsense transcripts homolog, UPF1.
Background: In eukaryotes, it is essential to have the ability to detect and degrade transcripts that lack full coding potential. Nonsense-mediated RNA decay (NMD) protects the organism by avoiding the translation of truncated peptides with dominant negative or deleterious gain-of-function potential. Rent1, a mammalian ortholog of Upflp, is essential for embryonic viability (13). Rent1 (also designated regulator of nonsense transcripts and HUpf1) contains an N-terminal zinc finger-like domain, NTPase domains and a region comprised of domains that define Rent1 as a superfamily group I helicase.
- 基因ID
- 5976
- 途径
- SARS-CoV-2 Protein Interactome
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