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Complexin 1 抗体 (AA 31-100)

Name: Complexin 1 抗体 (AA 31-100)
SKU: ABIN1385745
Availability: OutOfStock

CPLX1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Paraformaldehyde-fixed, paraffin embedded rat brain tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CPLX1 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (Complexin 1 抗体 (AA 31-100))

IHC (p)

IF (p)

Paraformaldehyde-fixed, paraffin embedded mouse brain tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CPLX1 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (Complexin 1 抗体 (AA 31-100))

IHC (p)

Paraformaldehyde-fixed, paraffin embedded tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-CPLX1 Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining (Complexin 1 抗体 (AA 31-100))

IF (p)

4 images

产品编号 ABIN1385745

发货至: 中国

Datasheet as PDF

抗原 See all Complexin 1 (CPLX1) 抗体

Complexin 1 (CPLX1)
抗原表位
14

14

8

7

6

6

1

1
AA 31-100
适用
36

25

23
小鼠, 大鼠
宿主
49

1

1

1
兔
Compatible Secondaries
克隆类型
52
多克隆
标记
14

6

4

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This Complexin 1 antibody is un-conjugated
应用范围
36

21

20

12

12

5

5

5

4

2

2

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

小鼠, 大鼠

预测反应

Human,Cow,Pig,Chicken

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CPLX1

亚型

IgG
anti-Complexin 1 (CPLX1) (AA 1-134) antibody
CPLX1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Complexin 1 (CPLX1) (N-Term) antibody
CPLX1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Complexin 1 (CPLX1) (AA 1-134) antibody
CPLX1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Complexin 1 (CPLX1) (AA 33-60) antibody
CPLX1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB23961 unconjugated

anti-Complexin 1 (CPLX1) (AA 1-134) antibody (PE)
CPLX1 适用: 人 IHC, ICC, IF, FACS 宿主: 兔 Polyclonal PE

anti-Complexin 1 (CPLX1) (AA 1-134) antibody (APC)
CPLX1 适用: 人 IHC, ICC, IF, FACS 宿主: 兔 Polyclonal APC

anti-Complexin 1 (CPLX1) (AA 39-69), (Middle Region) antibody
CPLX1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Complexin 1 (CPLX1) (AA 31-100) antibody (Biotin)
CPLX1 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin

anti-Complexin 1 (CPLX1) (AA 31-100) antibody (AbBy Fluor® 555)
CPLX1 适用: 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555

anti-Complexin 1 (CPLX1) (AA 31-100) antibody (AbBy Fluor® 350)
CPLX1 适用: 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

Complexin 1 (CPLX1)

别名

CPLX1 (CPLX1 产品)

别名

MGC84299 antibody, CPLX1 antibody, CPX-I antibody, CPX1 antibody, 921-S antibody, complexin 1 L homeolog antibody, complexin 1 antibody, cplx1.L antibody, CPLX1 antibody, cplx1 antibody, Cplx1 antibody

背景

Synonyms: complexin 1, Complexin I, Complexin-1, CPLX1, CPLX1_HUMAN, CPX I, CPX-I, CPX1, Synaphin 2, Synaphin-2, 921-S.
Background: Complexin 1 and Complexin 2, also designated Synaphin 1 and Synaphin 2, contain an a-helical middle domain of approximately 58 amino acids. Complexin 1 and Complexin 2 are expressed in presynaptic terminals of inhibitory and excitatory hippocampal neurons, respectively, and in cytoplasmic pools during early stages of development. Complexins promote SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) precomplex formation by binding to synaxin with its a-helical domain. Complexins are important regulators of transmitter release at a late step in calcium dependent neurotransmitter release or immediately after the calcium-triggering step of fast synchronous transmitter release and preceding vesicle fusion. Neurons lacking complexins show reduced transmitter release efficiency due to decreased calcium sensitivity of the synaptic secretion process. Complexin 2 may play a role in LTP (long term potentiation) following tetanic stimulation. A progressive loss of Complexin 2 occurs in the brains of mice carrying the Huntington disease mutation, an autosomal dominant neurodegenerative disorder. Changes in the neurotransmitter release might contribute to the motor, emotional and cognitive dysfunctions seen in these mice.

途径

Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport