DIS3L 抗体
-
- 抗原 See all DIS3L 抗体
- DIS3L (DIS3-Like Exonuclease 1 (DIS3L))
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This DIS3L antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DIS3L
- 亚型
- IgG
- Top Product
- Discover our top product DIS3L Primary Antibody
-
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 1-300) antibody
DIS3L 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 1-971) antibodyDIS3L 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 1-971) antibodyDIS3L 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DIS3-Like Exonuclease 1 (DIS3L) (AA 195-224), (N-Term) antibodyDIS3L 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB27115 unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- DIS3L (DIS3-Like Exonuclease 1 (DIS3L))
- 别名
- DIS3L (DIS3L 产品)
- 别名
- DIS3L1 antibody, AV340375 antibody, RGD1308959 antibody, zgc:158615 antibody, DIS3 like exosome 3'-5' exoribonuclease antibody, DIS3-like exosome 3'-5' exoribonuclease antibody, DIS3L antibody, dis3l antibody, Dis3l antibody, dis3l.L antibody
- 背景
-
Synonyms: DIS3 like exonuclease 1, DIS3 mitotic control homolog S. cerevisiae like, FLJ38088, KIAA1955, MGC4562, DI3L1_HUMAN.
Background: The exosome is a multi-protein complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3? regions. DIS3, also known as RRP44, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain. Widely expressed with highest expression in testis, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis. Multiple isoforms of DIS3 exist due to alternative splicing events.
- 基因ID
- 115752
-
