Influenza Nucleoprotein 抗体 (Influenza A Virus (A/Russia:St.Petersburg/8/2006)) (AA 71-170)
(1 reference)-
- 抗原 See all Influenza Nucleoprotein (NP) 抗体
- Influenza Nucleoprotein (NP)
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抗原表位
- AA 71-170
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适用
- Influenza A Virus, Virus
- Virus Strain
- A/Russia:St.Petersburg/8/2006
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- 非结合性
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- Virus
- 交叉反应 （详细）
- Influenza A virus
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from Influenza A virus (strain A/Russia:St.Petersburg/8/2006 H1N1) Nucleoprotein
- 亚型
- IgG
- Top Product
- Discover our top product NP Primary Antibody
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anti-Influenza Nucleoprotein antibody (Influenza A Virus H2N2) (H1N1), (H2N2), (H3N2), (H5N1), (H5N2)
NP 适用: Influenza A Virus H2N2 ELISA, WB, IF, IHC, IP, IC 宿主: 小鼠 Monoclonal C43 unconjugated
anti-Influenza Nucleoprotein antibody (Influenza A Virus H2N2) (H1N1), (H2N2), (H3N2), (H5N1), (H5N2) (HRP)NP 适用: Influenza A Virus H2N2 ELISA, WB, IHC, IC 宿主: 小鼠 Monoclonal C43 HRP
anti-Influenza Nucleoprotein antibody (Influenza B Virus) (HRP)NP 适用: Influenza B Virus ELISA 宿主: 小鼠 Monoclonal 3D7 HRP
anti-Influenza Nucleoprotein antibody (Influenza A Virus H2N2)NP 适用: Influenza A Virus H2N2 ELISA, WB 宿主: 小鼠 Monoclonal 9C11 unconjugated
anti-Influenza Nucleoprotein antibody (Influenza A Virus)NP 适用: Influenza A Virus ELISA 宿主: 小鼠 Monoclonal FluA-NP 2C9 unconjugated
anti-Influenza Nucleoprotein antibody (Influenza B Virus)NP 适用: Influenza B Virus ELISA 宿主: 小鼠 Monoclonal 1H7a unconjugated
anti-Influenza Nucleoprotein antibody (Influenza B Virus)NP 适用: Influenza B Virus ELISA 宿主: 小鼠 Monoclonal 3D7 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "All-in-one bacmids: an efficient reverse genetics strategy for influenza A virus vaccines." in: Journal of virology, Vol. 88, Issue 17, pp. 10013-25, (2014) (PubMed).
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: "All-in-one bacmids: an efficient reverse genetics strategy for influenza A virus vaccines." in: Journal of virology, Vol. 88, Issue 17, pp. 10013-25, (2014) (PubMed).
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- 抗原
- Influenza Nucleoprotein (NP)
- 别名
- Influenza A virus Nucleoprotein (NP 产品)
- 别名
- nucleoprotein antibody, NP antibody
- 物质类
- Influenza Protein
- 背景
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Synonyms: Nucleoprotein, NP, Nucleocapsid protein, Protein N, Influenza A virus H1N1, H3N2 Nucleoprotein, H9N2 Nucleoprotein, H2N2 Nucleoprotein, H3N8 Nucleoprotein, H7N7 Nucleoprotein, H5N1 Nucleoprotein.
Background: Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
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