AXDND1 抗体
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- 抗原 See all AXDND1 products
- AXDND1 (Axonemal Dynein Light Chain Domain Containing 1 (AXDND1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AXDND1 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human C1orf125
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- AXDND1 (Axonemal Dynein Light Chain Domain Containing 1 (AXDND1))
- 别名
- C1orf125 (AXDND1 产品)
- 别名
- C1orf125 antibody, RP11-215I23.2 antibody, 9430070O13Rik antibody, Gm979 antibody, axonemal dynein light chain domain containing 1 antibody, AXDND1 antibody, Axdnd1 antibody
- 背景
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Synonyms: axonemal dynein light chain domain containing 1, AXDN1_HUMAN, AXDND1, Axonemal dynein light chain domain-containing protein 1, DKFZp686H1423, hypothetical protein LOC126859, RP11-215I23.2.
Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf125 gene product has been provisionally designated C1orf125 pending further characterization.
- 基因ID
- 126859
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