TPD52L1 抗体
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- 抗原 See all TPD52L1 抗体
- TPD52L1 (Tumor Protein D52-Like 1 (TPD52L1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TPD52L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TPD52L1/D53
- 亚型
- IgG
- Top Product
- Discover our top product TPD52L1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- TPD52L1 (Tumor Protein D52-Like 1 (TPD52L1))
- 别名
- D53 (TPD52L1 产品)
- 别名
- d53 antibody, MGC84190 antibody, TPD52L1 antibody, zgc:110003 antibody, D53 antibody, hD53 antibody, tumor protein D52-like 1 antibody, tumor protein D52 like 1 L homeolog antibody, tumor protein D52 like 1 antibody, Tpd52l1 antibody, tpd52l1.L antibody, TPD52L1 antibody, tpd52l1 antibody
- 背景
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Synonyms: D53, D54, hD53, hD54, Tpd52l1, TPD52L2 TPD53_HUMAN, Tumor protein D52 like 1, Tumor protein D52 like 2, Tumor protein D52-like 1, Tumor protein D53, Tumor protein D54.
Background: The cell commits to dividing during the G2/M phase transition, and the timing of mitotic entry is tightly regulated to guarantee correct chromosome segregation. D53, also referred to as tumor protein D52-like 1 (TPD52L1), is a coiled-coil motif-bearing member of the D52 tumor protein family. D53 intereacts with 14-3-3, a negative regulator of the G2/M transition, in breast cancer cells. Expression of D53 is highly upregulated at the G2/M phase transition in breast cancer cell lines, and deregulated expression of this protein can adversely affect the completion of mitosis. D53 may function as a signaling intermediate and/or regulator of vesicle trafficking and cell proliferation.
- 基因ID
- 7164
- 途径
- Positive Regulation of Endopeptidase Activity
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