LRSAM1 抗体
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- 抗原 See all LRSAM1 抗体
- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRSAM1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human LRSAM1
- 亚型
- IgG
- Top Product
- Discover our top product LRSAM1 Primary Antibody
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anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-723) antibody
LRSAM1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-290) antibodyLRSAM1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-723) antibodyLRSAM1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (Internal Region) antibodyLRSAM1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-30), (N-Term) antibodyLRSAM1 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB32441 unconjugated
anti-Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) (AA 1-30), (N-Term) antibodyLRSAM1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- LRSAM1 (Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1))
- 别名
- LRSAM1 (LRSAM1 产品)
- 别名
- CMT2P antibody, RIFLE antibody, TAL antibody, leucine rich repeat and sterile alpha motif containing 1 antibody, LRSAM1 antibody, Lrsam1 antibody
- 背景
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Synonyms: E3 ubiquitin protein ligase LRSAM1, hTAL, Leucine rich repeat and sterile alpha mot containing protein 1, RLE, TAL, Tsg101 associated ligase, LRSM1_HUMAN.
Background: LRSAM1 is an E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivation of the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos. It selectively regulates cell adhesion molecules and plays a role in receptor endocytosis and viral budding. LRSAM1 contains a RING-type zinc finger, 5 leucine-rich repeats and 1 SAM (sterile alpha motif) domain. The coiled coil domains interact with the SB domain of TSG101. The PTAP motifs mediate the binding to UEV domains. There are 3 isoforms produced by alternative splicing.
- 基因ID
- 90678
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