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UBR2 抗体

UBR2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385352
发货至: 中国
  • 抗原 See all UBR2 抗体
    UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
    适用
    • 42
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    人, 小鼠, 大鼠
    宿主
    • 37
    • 4
    • 1
    克隆类型
    • 39
    • 3
    多克隆
    标记
    • 18
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    This UBR2 antibody is un-conjugated
    应用范围
    • 29
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    • 5
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    • 1
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    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human UBR2
    亚型
    IgG
    Top Product
    Discover our top product UBR2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
    别名
    UBR2 (UBR2 产品)
    别名
    ba49a4.1 antibody, si:ch211-239i4.2 antibody, C6orf133 antibody, RP3-392M17.3 antibody, bA49A4.1 antibody, dJ242G1.1 antibody, dJ392M17.3 antibody, 9930021A08Rik antibody, AI462103 antibody, AW540746 antibody, E130209G04Rik antibody, mKIAA0349 antibody, ubiquitin protein ligase E3 component n-recognin 2 antibody, ubiquitin protein ligase E3 component n-recognin 2 S homeolog antibody, UBR2 antibody, ubr2 antibody, ubr2.S antibody, Ubr2 antibody
    背景

    Synonyms: E3 ubiquitin protein ligase UBR2, N recognin 2, Ubiquitin ligase E3 alpha II, Ubiquitin protein ligase E3 alpha 2, Ubiquitin protein ligase E3 component n recognin 2, UBR 2, UBR2_HUMAN, N-recognin-2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.

    基因ID
    23304
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