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BAGE2 抗体

BAGE2 适用: 人 IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385347
发货至: 中国
  • 抗原 See all BAGE2 products
    BAGE2 (B Melanoma Antigen Family, Member 2 (BAGE2))
    适用
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
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    This BAGE2 antibody is un-conjugated
    应用范围
    • 12
    • 4
    • 3
    • 2
    • 2
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human BAGE2
    亚型
    IgG
  • 应用备注
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    BAGE2 (B Melanoma Antigen Family, Member 2 (BAGE2))
    别名
    BAGE2 (BAGE2 产品)
    别名
    CT2.2 antibody, BAGE family member 2 antibody, BAGE2 antibody
    背景

    Synonyms: B melanoma antigen 2, B melanoma antigen family, member 2, Cancer/testis antigen 2.2, CT2.2, BAGE2_HUMAN.

    Background: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22 % of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.

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