CECR1 抗体 (AA 450-500)
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- 抗原 See all CECR1 抗体
- CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1))
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抗原表位
- AA 450-500
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CECR1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CECR1/ADGF
- 亚型
- IgG
- Top Product
- Discover our top product CECR1 Primary Antibody
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anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (AA 30-511) antibody
CECR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (AA 402-511) antibodyCECR1 适用: 人 WB, IP, ELISA 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) antibodyCECR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (AA 1-270) antibodyCECR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (AA 1-270) antibodyCECR1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (AA 144-193) antibodyCECR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (AA 1-270) antibodyCECR1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1) (N-Term) antibodyCECR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- CECR1 (Cat Eye Syndrome Chromosome Region, Candidate 1 (CECR1))
- 别名
- CECR1 (CECR1 产品)
- 别名
- cecr1 antibody, fj65e02 antibody, wu:fj65e02 antibody, CECR1 antibody, ADA2 antibody, ADGF antibody, IDGFL antibody, adenosine deaminase 2a antibody, cat eye syndrome chromosome region, candidate 1 antibody, adenosine deaminase 2 antibody, adenosine deaminase 2 L homeolog antibody, ada2a antibody, CECR1 antibody, ADA2 antibody, ada2.L antibody
- 背景
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Synonyms: ADGF, Cat eye syndrome chromosome region candidate 1, Cat eye syndrome critical region protein 1, Cat eye syndrome critical region protein 1 precursor, CECR 1, IDGFL, CECR1_HUMAN.
Background: CECR1 is a member of the adenosine and AMP deaminases family. It may act as a growth factor and have adenosine deaminase activity. It is a candidate gene for cat eye syndrome. Two transcript variants encoding distinct isoforms have been identified for this gene.Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.
- 基因ID
- 51816
- UniProt
- Q9NZK5
- 途径
- Ribonucleoside Biosynthetic Process
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