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LRRC59 抗体 (AA 21-120)

LRRC59 适用: 小鼠, 大鼠 WB, IHC (p), ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385303
发货至: 中国
  • 抗原 See all LRRC59 抗体
    LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 13
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 13
    克隆类型
    • 13
    多克隆
    标记
    • 13
    This LRRC59 antibody is un-conjugated
    应用范围
    • 13
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human LRRC59
    亚型
    IgG
    Top Product
    Discover our top product LRRC59 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    LRRC59 (Leucine Rich Repeat Containing 59 (LRRC59))
    别名
    LRRC59 (LRRC59 产品)
    别名
    p34 antibody, PRO1855 antibody, AA959742 antibody, C78668 antibody, leucine rich repeat containing 59 antibody, leucine rich repeat containing 59 S homeolog antibody, LRRC59 antibody, Lrrc59 antibody, lrrc59.S antibody
    背景

    Synonyms: Leucine-rich repeat-containing protein 59, LRC59_HUMAN, LRRC59, PRO1855.

    Background: LRRC59 (leucine rich repeat containing 59), also known as PRO1855, is a 307 amino acid protein that contains leucine-rich repeats and may play a role in protein binding events throughout the cell. The gene encoding LRRC59 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    基因ID
    55379
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