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TAS2R60 抗体 (AA 41-140)

TAS2R60 适用: 小鼠 WB, ELISA, IHC (fro), IHC (p), ICC, IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385223
发货至: 中国
  • 抗原 See all TAS2R60 抗体
    TAS2R60 (Taste Receptor, Type 2, Member 60 (TAS2R60))
    抗原表位
    AA 41-140
    适用
    小鼠
    宿主
    • 8
    克隆类型
    • 8
    多克隆
    标记
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TAS2R60 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Bee
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human T2R60
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    TAS2R60 (Taste Receptor, Type 2, Member 60 (TAS2R60))
    别名
    T2R60 (TAS2R60 产品)
    别名
    T2R56 antibody, Bota-T2R56 antibody, T2R60 antibody, taste 2 receptor member 60 antibody, TAS2R60 antibody
    背景

    Synonyms: T2R56, TAS2R60, Taste receptor type 2 member 60, T2R60_HUMAN.

    Background: T2R60 is a 318 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor T2R family. T2R60 acts as a receptor that may play a role in the perception of bitterness, and is also thought to be involved in sensing the chemical composition of gastrointestinal content. As a gustducin-linked receptor, the activity of T2R60 may stimulate G alpha (alpha gustducin), mediate PLC beta 2 activation and lead to the gating of TRPM5. While expressed in subsets of taste receptor cells of the tongue and palate epithelium, T2R60 is found exclusively in gustducin-positive cells. The gene that encodes T2R60 contains 957 bases and maps to human chromosome 7q35. Chromosome 7 houses over 1,000 genes, comprises nearly 5 % of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

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