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RAB3GAP1 抗体 (AA 501-600)

RAB3GAP1 适用: 人 ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1385218
发货至: 中国
  • 抗原 See all RAB3GAP1 抗体
    RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))
    抗原表位
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    适用
    • 14
    • 3
    • 2
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 10
    • 2
    • 1
    • 1
    This RAB3GAP1 antibody is un-conjugated
    应用范围
    • 10
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human RAB3GAP1
    亚型
    IgG
    Top Product
    Discover our top product RAB3GAP1 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))
    别名
    RAB3GAP1 (RAB3GAP1 产品)
    别名
    1700003B17Rik antibody, 4732493F09Rik antibody, AL117896 antibody, Rab3gap antibody, p130 antibody, P130 antibody, RAB3GAP antibody, RAB3GAP130 antibody, WARBM1 antibody, RAB3 GTPase activating protein subunit 1 antibody, RAB3 GTPase activating protein catalytic subunit 1 antibody, Rab3gap1 antibody, RAB3GAP1 antibody
    背景

    Synonyms: DKFZp434A012, KIAA0066, P130, Rab3 GAP, Rab3 GAP p130, RAB3 GTPase activating protein 130 kDa subunit, Rab3 GTPase activating protein catalytic subunit, RAB3GAP, RAB3GAP130, WARBM1, RB3GP_HUMAN.

    Background: Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab 3 GAP p130, also known as Rab3 GTPase-activating protein catalytic subunit, is a 981 amino acid protein that belongs to the Rab3-GAP catalytic subunit family. Rab 3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP, and is required for normal eye and brain development. Defects in Rab 3 GAP p130 are the cause of Warburg micro syndrome 1 (WARBM1). WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia. The Rab 3 GAP p130 protein may participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters. Existing as two alternatively spliced isoforms, the Rab 3 GAP p130 gene is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish and fruit fly, and maps to human chromosome 2q21.3.

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