-
- 抗原 See all TNFRSF10B 抗体
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This TNFRSF10B antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), ELISA, Functional Studies (Func)
- 特异性
- Recognises a 42-46 kDa protein
- 纯化方法
- Ion exchange chromatography
- 过滤
- 0.22 μm filtered
- 免疫原
- Recombinant human TRAIL R2/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells
- 克隆位点
- B-K29
- 亚型
- IgG1 kappa
- Biological Activity Comment
- Neutralizes TRAIL induced apoptosis of U937 cell line
- Top Product
- Discover our top product TNFRSF10B Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
- 储存液
- Without preservative
- 储存条件
- 4 °C
- 储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
-
-
Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8030-9, (2008) (PubMed).
: "TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque." in: The Journal of experimental medicine, Vol. 203, Issue 1, pp. 239-50, (2006) (PubMed).
: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).
: "
-
Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8030-9, (2008) (PubMed).
-
- 抗原
- TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
- 别名
- TRAIL R2 (TNFRSF10B 产品)
- 别名
- TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
- 背景
- DR5, TRAIL R2
- 分子量
- 42-46 kDa
- 途径
- p53 Pathway, Apoptosis, Positive Regulation of Endopeptidase Activity
-