IL-6 Receptor 抗体
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- 抗原 See all IL-6 Receptor (IL6R) 抗体
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL-6 Receptor antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein
- 纯化方法
- Ion exchange chromatography
- 过滤
- 0.22 μm filtered
- 免疫原
- gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
- 克隆位点
- B-R6
- 亚型
- IgG1 kappa
- Biological Activity Comment
- Inhibits IL-6 induced proliferation of XG-1 cells
- Top Product
- Discover our top product IL6R Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
- 储存液
- Without preservative
- 储存条件
- 4 °C
- 储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma." in: The hematology journal : the official journal of the European Haematology Association / EHA, Vol. 2, Issue 1, pp. 42-53, (2002) (PubMed).
: "IL-4 prevents the blockade of dendritic cell differentiation induced by tumor cells." in: Cancer research, Vol. 61, Issue 7, pp. 3096-104, (2001) (PubMed).
: "STAT3 is constitutively activated in Hodgkin cell lines." in: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).
: "Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors." in: Leukemia, Vol. 14, Issue 1, pp. 188-97, (2000) (PubMed).
: "Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor." in: Blood, Vol. 92, Issue 12, pp. 4778-91, (1999) (PubMed).
: "Toward a role of dendritic cells in the germinal center reaction: triggering of B cell proliferation and isotype switching." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 6, pp. 3428-36, (1999) (PubMed).
: "Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 5, pp. 2223-31, (1998) (PubMed).
: "Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants." in: Immunology, Vol. 91, Issue 2, pp. 303-13, (1997) (PubMed).
: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." in: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).
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Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma." in: The hematology journal : the official journal of the European Haematology Association / EHA, Vol. 2, Issue 1, pp. 42-53, (2002) (PubMed).
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- 抗原
- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
- 别名
- CD126 (IL6R 产品)
- 别名
- IL6R antibody, il-6ra antibody, CD126 antibody, IL-6R-1 antibody, IL-6RA antibody, IL6Q antibody, IL6RA antibody, IL6RQ antibody, gp80 antibody, IL6R1 antibody, Il6ra antibody, IL-6Ralpha antibody, IL-6R antibody, Il6r antibody, interleukin 6 receptor antibody, interleukin 6 receptor, alpha antibody, IL6R antibody, il6r antibody, Il6r antibody, Il6ra antibody
- 背景
- IL-6R / gp80
- 分子量
- 80 kDa
- 途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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