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LGR4 抗体

LGR4 适用: 人, 小鼠 FACS, cELISA 宿主: 大鼠 Monoclonal BBX-3A8 unconjugated
产品编号 ABIN1381741
发货至: 中国
  • 抗原 See all LGR4 抗体
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    适用
    • 33
    • 11
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    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 25
    • 5
    • 3
    大鼠
    克隆类型
    • 25
    • 8
    单克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGR4 antibody is un-conjugated
    应用范围
    • 12
    • 11
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    Flow Cytometry (FACS), Cell-ELISA (cELISA)
    特异性
    Anti-human LGR4
    交叉反应
    小鼠
    产品特性
    Selection: Based on recognition of the complete native protein expressed on transfected mammalian cells
    纯化方法
    Protein G
    免疫原
    genetic immunisation with cDNA encoding human LGR4
    克隆位点
    BBX-3A8
    亚型
    IgG2a kappa
    Top Product
    Discover our top product LGR4 Primary Antibody
  • 应用备注
    Flow cytometry: 1.2 µg/10^6 cells
    CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    说明

    Synonyms: GPR48

    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    short term: 2 °C - 8 °C, long term: -20 °C
  • 抗原
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    别名
    LGR4 (LGR4 产品)
    别名
    BNMD17 antibody, GPR48 antibody, 9130225G07 antibody, A330106J01Rik antibody, A930009A08Rik antibody, Gpr48 antibody, leucine rich repeat containing G protein-coupled receptor 4 antibody, leucine-rich repeat-containing G protein-coupled receptor 4 antibody, LGR4 antibody, Lgr4 antibody
    背景
    LGR4 (Leucine-rich repeat- containing G protein-coupled receptor 4, GPR48) belongs to the superfamily of G protein-coupled receptors (GPCRs). It is a 951 amino acid multi-pass membrane protein and has multiple N-terminal leucine-rich repeats, which are important for interaction with the glycoprotein ligands, and 7 transmembrane domains. LGR4 is highly expressed in the adult human pancreas but also with moderate levels of expression in placenta, kidney, brain and heart. LGR4 functions as an orphan receptor that may be involved in physiologic activities throughout the cell. It is overexpressed in various cancer types and is thought to enhance carcinoma invasiveness and metastasis, suggesting an important role in tumor progression.
    UniProt
    Q9BXB1
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