我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

LAMP2 抗体

Name: LAMP2 抗体
Brand: antibodies-online
SKU: ABIN135832
Availability: OutOfStock

LAMP2 适用: 人 IHC, FACS 宿主: 小鼠 Monoclonal H4B4 unconjugated

RA differentiated SH-SY5Y neuroblastoma cells were stained with Mouse Anti-Human CD107b-UNLB (LAMP2 抗体)

1 image

(5 references)

产品编号 ABIN135832

发货至: 中国

Datasheet as PDF

抗原 See all LAMP2 抗体

LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))
适用
116

73

33

16

3

3

2

1
人
宿主
88

42

31
小鼠
Compatible Secondaries
克隆类型
81

79
单克隆
标记
55

22

18

15

12

8

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This LAMP2 antibody is un-conjugated
应用范围
112

55

54

41

29

26

25

13

13

12

11

7

5

3

1

1
Immunohistochemistry (IHC), Flow Cytometry (FACS)

特异性

Human/Rhesus/African Green Monkey CD107b, Mr 100-120 kDa

产品特性

Mouse Anti-Human CD107b-UNLB

纯化方法

Purified

免疫原

Human adherent peripheral blood cells

克隆位点

H4B4

亚型

IgG1

Top Product

Discover our top product LAMP2 Primary Antibody
anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 191-362) antibody
LAMP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-168) antibody
LAMP2 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 6A10H10 unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 29-168) antibody
LAMP2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 8E2F2 unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 301-411) antibody
LAMP2 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IHC (fro), IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 193-375) antibody
LAMP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibody
LAMP2 适用: 人 WB, FACS, ICC, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal H4B4 unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) antibody
KO Validated LAMP2 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 54-268) antibody
LAMP2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (AA 30-127) antibody
LAMP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G10 unconjugated

anti-Lysosomal-Associated Membrane Protein 2 (LAMP2) (C-Term) antibody
LAMP2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

样本量

1 mL

限制

仅限研究用
缓冲液

Product is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.

注意事项

Each reagent is stable for the period shown on the bottle label if stored as directed.

储存条件

4 °C
Eriksson, Wäster, Öllinger: "Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins." in: Cell death & disease, Vol. 11, Issue 5, pp. 370, (2020) (PubMed).

Wäster, Eriksson, Vainikka, Rosdahl, Öllinger: "Extracellular vesicles are transferred from melanocytes to keratinocytes after UVA irradiation." in: Scientific reports, Vol. 6, pp. 27890, (2016) (PubMed).

Boman, Svensson, Boxer, Rojas, Seeley, Karydas, Miller, Kågedal, Svenningsson: "Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid." in: Journal of Parkinson's disease, Vol. 6, Issue 2, pp. 307-15, (2016) (PubMed).

Fritsch, Stephan, Tchikov, Winoto-Morbach, Gubkina, Kabelitz, Schütze: "Cell Fate Decisions to TNF Regulated by K63 Ubiquitination of TNF-Receptor 1." in: Molecular and cellular biology, (2014) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).
抗原

LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

别名

CD107b (LAMP2 产品)

别名

CD107b antibody, LAMP-2 antibody, LAMPB antibody, LGP110 antibody, Lamp-2 antibody, Lamp-2a antibody, Lamp-2b antibody, Lamp-2c antibody, Mac3 antibody, cd107b antibody, lamp-2 antibody, lampb antibody, LAMP2 antibody, lamp2 antibody, DKFZp459J126 antibody, LGP-B antibody, sb:cb587 antibody, wu:fb14a06 antibody, zgc:103532 antibody, lysosomal associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 antibody, lysosomal-associated membrane protein 2 S homeolog antibody, lysosomal membrane glycoprotein 2 antibody, LAMP2 antibody, Lamp2 antibody, lamp2.S antibody, lamp2 antibody

背景

CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium.

途径

Autophagy