我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

LAMP1 抗体

Name: LAMP1 抗体
Brand: antibodies-online
SKU: ABIN135831
Availability: OutOfStock

LAMP1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal H4A3 unconjugated

Human T cell leukemia cell line Jurkat was intracellularly stained with Mouse Anti-Human CD107a-PE. (LAMP1 抗体)

FACS

1 image

(4 references)

产品编号 ABIN135831

发货至: 中国

Datasheet as PDF

抗原 See all LAMP1 抗体

LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
适用
98

59

38

27

8

3

3

3

2

2

1

1

1
人
宿主
61

54

18

1
小鼠
Compatible Secondaries
克隆类型
80

54
单克隆
标记
47

15

13

12

7

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This LAMP1 antibody is un-conjugated
应用范围
85

67

43

29

25

24

22

13

13

13

13

3

3

2

2

2

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC)

特异性

Human/Rhesus/African Green Monkey/Pigtail Macaque/Sooty Mangabey CD107a, Mr 100-120 kDa

产品特性

Mouse Anti-Human CD107a-UNLB

纯化方法

Purified

免疫原

Human adherent peripheral blood cells

克隆位点

H4A3

亚型

IgG1

Top Product

Discover our top product LAMP1 Primary Antibody
anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 80-280) antibody
LAMP1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 301-417) antibody
LAMP1 适用: 人, 小鼠, 大鼠, 猴 WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 49-297) antibody
LAMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 人, 小鼠, Non-Human Primate WB, FACS, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal Ly1C6 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 125-154) antibody
LAMP1 适用: 人, 小鼠 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 人, 小鼠, 灵长类 WB, FACS, IHC, ICC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal H4A3 unconjugated

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (FITC)
LAMP1 适用: 小鼠 WB, FACS, IHC, IP, IHC (p), IHC (fro) 宿主: 大鼠 Monoclonal FITC

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody (APC)
LAMP1 适用: 人, 小鼠, Non-Human Primate FACS 宿主: 小鼠 Monoclonal H4A3 APC

anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) antibody
LAMP1 适用: 人, Green Monkey WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 3C3 unconjugated

应用备注

Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

样本量

1 mL

限制

仅限研究用
缓冲液

Product is supplied as 0.1 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.

注意事项

Each reagent is stable for the period shown on the bottle label if stored as directed.

储存条件

4 °C
Eriksson, Wäster, Öllinger: "Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins." in: Cell death & disease, Vol. 11, Issue 5, pp. 370, (2020) (PubMed).

Remacle, Hullugundi, Dolkas, Angert, Cieplak, Scott, Chernov, Shubayev, Strongin: "Interaction of the cryptic fragment of myelin basic protein with mitochondrial voltage-dependent anion-selective channel-1 affects cell energy metabolism." in: The Biochemical journal, Vol. 475, Issue 14, pp. 2355-2376, (2019) (PubMed).

Boman, Svensson, Boxer, Rojas, Seeley, Karydas, Miller, Kågedal, Svenningsson: "Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid." in: Journal of Parkinson's disease, Vol. 6, Issue 2, pp. 307-15, (2016) (PubMed).

Armstrong, Mattsson, Appelqvist, Janefjord, Sandin, Agholme, Olsson, Svensson, Blennow, Zetterberg, Kågedal: "Lysosomal network proteins as potential novel CSF biomarkers for Alzheimer's disease." in: Neuromolecular medicine, Vol. 16, Issue 1, pp. 150-60, (2014) (PubMed).
抗原

LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

别名

CD107a (LAMP1 产品)

别名

CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody

背景

CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes the major sialoglycoproteins on lysosomal membranes. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is expressed by granulocytes, T cells, macrophages, dendritic cells, activated platelets, tonsillar epithelium and some tumor cell lines, including U937 and KG1a. It is also a widely expressed intracellular antigen. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases. The upregulation of both CD107a and CD107b on the surface of tumor cell lines has been associated with their enhanced metastatic potential, where they may increase adhesion to extracellular matrix and endothelium.

途径

Autophagy