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- 抗原 See all LAMP1 抗体
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This LAMP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 特异性
- Mouse CD107a, Mr 110-140 kDa
- 产品特性
- Rat Anti-Mouse CD107a-UNLB
- 纯化方法
- Purified
- 免疫原
- Plasma membrane fraction of mouse embryo NIH/3T3 cell line
- 克隆位点
- 1D4B
- 亚型
- IgG2a
- Top Product
- Discover our top product LAMP1 Primary Antibody
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- 应用备注
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Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. - 说明
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Immunoelectron microscopy, Immunoaffinity chromatography
- 样本量
- 1 mL
- 限制
- 仅限研究用
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- 缓冲液
- Product is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- 4 °C
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Deletion of the murine scavenger receptor CD68." in: Journal of lipid research, Vol. 52, Issue 8, pp. 1542-50, (2011) (PubMed).
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Deletion of the murine scavenger receptor CD68." in: Journal of lipid research, Vol. 52, Issue 8, pp. 1542-50, (2011) (PubMed).
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- 抗原
- LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))
- 别名
- CD107a (LAMP1 产品)
- 别名
- CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
- 背景
- CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion. CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.
- 途径
- Autophagy
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