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CD86 抗体

CD86 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 2D10 unconjugated
产品编号 ABIN135433
发货至: 中国
  • 抗原 See all CD86 抗体
    CD86
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
    • 153
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    单克隆
    标记
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    This CD86 antibody is un-conjugated
    应用范围
    • 153
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    Flow Cytometry (FACS)
    特异性
    Mouse CD86, Mr 80 kDa
    产品特性
    Rat Anti-Mouse CD86-LE/AF
    纯化方法
    Ion exchange column
    内毒素水平
    Low endotoxin
    免疫原
    Mouse B cell lymphoma cell line 5C2
    克隆位点
    2D10
    亚型
    IgG2b
    Top Product
    Discover our top product CD86 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature , Sep - Reported in literature , CMCD - Reported in literature , ELISA - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, SPRD, and PE/CY7 conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vivo and in vitro blocking assays, Identification of CD86+ cells in frozen section

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原
    CD86
    别名
    CD86 (CD86 产品)
    别名
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    背景
    CD86/B7-2 is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80/B7-1, CD86 participates in T cell costimulation via interaction with CD28 and CD152/CTLA-4. It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes and dendritic cells. Since CD86/B7-2 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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