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IL2 Receptor beta 抗体

IL2RB 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 5H4 unconjugated
产品编号 ABIN135408
发货至: 中国
  • 抗原 See all IL2 Receptor beta (IL2RB) 抗体
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    适用
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    小鼠
    宿主
    • 78
    • 29
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    大鼠
    克隆类型
    • 79
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    单克隆
    标记
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    This IL2 Receptor beta antibody is un-conjugated
    应用范围
    • 70
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    Flow Cytometry (FACS)
    特异性
    Mouse CD122, 90-100 kDa
    交叉反应 (详细)
    Cross-reactivity with Stat1 from other sources has not been determined.
    预测反应
    A BLAST analysis was used to suggest cross-reactivity with Stat1 from mouse and rat based on 100% homology with the immunizing sequence. Partial reactivity is expected against Stat1 from human sources as 90% homology is noted.
    产品特性
    Rat Anti-Mouse CD122-UNLB
    纯化方法
    Purified
    免疫原
    Rat myeloma YB2/0 transfected with truncated IL-2Rbeta cDNA (YB2/0-mbetat-28)
    克隆位点
    5H4
    亚型
    IgG2a
    Top Product
    Discover our top product IL2RB Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IP - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE and APC conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    别名
    CD122 (IL2RB 产品)
    别名
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    背景
    The IL-2 receptor is a complex of three distinct polypeptide chains: (i) the chain which binds IL-2 with low affinity, (ii) the chain that binds IL-2 with high affinity, and (ii) the common chain (C) that does not bind IL-2. The high affinity receptor complex is an α/β/γ heterotrimer with a kDa of 1.3 x 10-11 M.2 In mouse spleen, CD122 is expresed on 30 % of CD8+ cells and all NK cells, but < 1 % of B cells and CD4+ T lymphocytes. In the thymus, its expression is confined to CD4-CD8+ single positive and CD4-CD8- double negative cells. Cytoplasmic regions of the IL-2R chain are involved in IL-2-mediated cellular signaling and, via the interaction of IL-2 and its receptor complex, may be involved in the generation and differentiation of T lymphocytes.
    途径
    JAK/STAT Signaling, Growth Factor Binding
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