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NK-1.1/CD161c 抗体

适用: 小鼠 FACS 宿主: 小鼠 Monoclonal PK136 unconjugated
产品编号 ABIN135344
发货至: 中国
  • 抗原 See all NK-1.1/CD161c products
    NK-1.1/CD161c (NK-1.1)
    适用
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    小鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This NK-1.1/CD161c antibody is un-conjugated
    应用范围
    • 51
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    Flow Cytometry (FACS)
    特异性
    Mouse NK1.1, Mr 39 kDa
    产品特性
    Mouse Anti-Mouse NK1.1-LE/AF
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
    内毒素水平
    Low endotoxin
    免疫原
    CE mouse spleen enriched for NK-1+ cells and bone marrow cells
    克隆位点
    PK136
    亚型
    IgG2a
  • 应用备注
    • Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , Depletion - Reported in literature , CMCD - Reported in literature , Block - Reported in literature , Activ - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, PACBLU, AF488, and AF700 conjugates 1 g/106 cells PE and APC conjugates 0.5 g/106 cells PE/CY7 and AF647 conjugates 0.3 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    Induction of proliferation of a subset of NK cells, In vivo depletion of NK1.1 cells, In vitro redirected lysis, In vitro cytotoxicity assays

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原
    NK-1.1/CD161c (NK-1.1)
    别名
    NK1.1 (NK-1.1/CD161c 产品)
    别名
    AI462337 antibody, CD161 antibody, Ly-59 antibody, Ly55c antibody, Ly59 antibody, NK-RP1 antibody, NK1.1 antibody, NKR-P1.9 antibody, NKRP1 antibody, NKRP140 antibody, Nk-1 antibody, Nk-1.2 antibody, Nk1 antibody, Nk1.2 antibody, Nkrp1c antibody, ly-55c antibody, killer cell lectin-like receptor subfamily B member 1C antibody, Klrb1c antibody
    背景
    NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL, NZB). NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.
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