CD86 抗体
-
- 抗原 See all CD86 抗体
- CD86
-
适用
- 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This CD86 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse CD86, Mr 80 kDa
- 产品特性
- Rat Anti-Mouse CD86-LE/AF
- 纯化方法
- Ion exchange column
- 内毒素水平
- Low endotoxin
- 免疫原
- LPS-activated CBA/Ca mouse spleen B cells
- 克隆位点
- GL1
- 亚型
- IgG2a
- Top Product
- Discover our top product CD86 Primary Antibody
-
-
- 应用备注
-
- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, PE/CY7, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- 说明
-
In vivo and in vitro blocking assays
- 样本量
- 1 mL
- 限制
- 仅限研究用
-
- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of PBS
- 储存液
- Azide free
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- -20 °C
- 储存方法
- Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
-
- 抗原
- CD86
- 别名
- CD86 (CD86 产品)
- 别名
- B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
- 背景
- CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
-