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CD86 抗体

CD86 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal GL1 unconjugated
产品编号 ABIN135273
发货至: 中国
  • 抗原 See all CD86 抗体
    CD86
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    小鼠
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    大鼠
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    • 154
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    单克隆
    标记
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    This CD86 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    特异性
    Mouse CD86, Mr 80 kDa
    产品特性
    Rat Anti-Mouse CD86-UNLB
    纯化方法
    Purified
    免疫原
    LPS-activated CBA/Ca mouse spleen B cells
    克隆位点
    GL1
    亚型
    IgG2a
    Top Product
    Discover our top product CD86 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, PE/CY7, AF647, and AF700 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vivo and in vitro blocking assays

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • Ma, Martínez-Ramírez, Borders, Gao, Sosa-Pineda: "Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts." in: eLife, Vol. 9, (2020) (PubMed).

  • 抗原
    CD86
    别名
    CD86 (CD86 产品)
    别名
    B7-2 antibody, B7.2 antibody, B70 antibody, CD28LG2 antibody, LAB72 antibody, B7 antibody, CLS1 antibody, Cd28l2 antibody, ETC-1 antibody, Ly-58 antibody, Ly58 antibody, MB7 antibody, MB7-2 antibody, TS/A-2 antibody, CD86 molecule antibody, CD86 antigen antibody, integrin subunit alpha 2b antibody, CD86 antibody, Cd86 antibody, Itga2b antibody
    背景
    CD86, also known as B7-2, is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B-cell specific stimuli with peak expression at 18-42 hours after stimulation. CD86, along with CD80/B7-1, is an important accessory molecule in T cell costimulation via its interaction with CD28 and CD152/CTLA-4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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