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CD80 抗体

CD80 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 1G10 unconjugated
产品编号 ABIN135268
发货至: 中国
  • 抗原 See all CD80 抗体
    CD80
    适用
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    小鼠
    宿主
    • 92
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    大鼠
    克隆类型
    • 129
    • 82
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    单克隆
    标记
    • 86
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    This CD80 antibody is un-conjugated
    应用范围
    • 125
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    Flow Cytometry (FACS)
    特异性
    Mouse CD80, Mr 52-55 kDa
    产品特性
    Rat Anti-Mouse CD80-UNLB
    纯化方法
    Purified
    免疫原
    Activated 5C2 cells
    克隆位点
    1G10
    亚型
    IgG2a
    Top Product
    Discover our top product CD80 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IP - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vivo and in vitro blocking of ligand binding

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    CD80
    别名
    CD80 (CD80 产品)
    别名
    B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
    背景
    CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours post-activation. The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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