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CD69 抗体 (FITC)

CD69 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal H1-2F3 FITC
产品编号 ABIN135255
发货至: 中国
  • 抗原 See all CD69 抗体
    CD69
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    小鼠
    宿主
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This CD69 antibody is conjugated to FITC
    应用范围
    • 114
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    Flow Cytometry (FACS)
    特异性
    Mouse CD69, Mr 85 kDa (unreduced)
    产品特性
    Hamster Anti-Mouse CD69-FITC
    纯化方法
    Protein A
    免疫原
    Mouse dendritic epidermal cell line Y245
    克隆位点
    H1-2F3
    亚型
    IgG
    Top Product
    Discover our top product CD69 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , Costim - Reported in literature , Activ - Reported in literature
    • Working Dilutions: Flow Cytometry FITC, BIOT, and AF488 conjugates 1 g/106 cells PE, APC, SPRD, PE/CY7, AF647, and PACBLU conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vitro T cell and NK-cell activation

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg in 1.0 mL of PBS/Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect conjugated products from light.
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • Waaler, Mygland, Tveita, Strand, Solberg, Olsen, Aizenshtadt, Fauskanger, Lund, Brinch, Lycke, Dybing, Nygaard, Bøe, Heintz, Hovig, Hammarström, Corthay, Krauss: "Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models." in: Communications biology, Vol. 3, Issue 1, pp. 196, (2020) (PubMed).

  • 抗原
    CD69
    别名
    CD69 (CD69 产品)
    别名
    5830438K24Rik antibody, AI452015 antibody, AIM antibody, VEA antibody, BL-AC/P26 antibody, CLEC2C antibody, EA1 antibody, GP32/28 antibody, MLR-3 antibody, Cd69 molecule antibody, CD69 antigen antibody, CD69 molecule antibody, Cd69 antibody, CD69 antibody
    背景
    CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa. It is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules. CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils. Although not detectable on resting lymphocytes, its expression is rapidly (within 2 hours) upregulated upon activation of T, B and NK cells, and neutrophils.4 Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.
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