CD38 抗体
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- 抗原 See all CD38 抗体
- CD38
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD38 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 特异性
- Mouse CD38, Mr 42 kDa
- 产品特性
- Rat Anti-Mouse CD38-UNLB
- 纯化方法
- Purified
- 免疫原
- BCL1 plasma membrane glycoproteins
- 克隆位点
- NIMR-5
- 亚型
- IgG2a
- Top Product
- Discover our top product CD38 Primary Antibody
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anti-CD38 (AA 1-300) antibody
适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 46-300) antibody适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (AA 43-300) antibody适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 5C5C3 unconjugated
anti-CD38 (AA 241-270), (C-Term) antibody适用: 人 FACS, WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18001 unconjugated
anti-CD38 (AA 241-270) antibody适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD38 (Internal Region) antibody适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD38 antibody适用: 人 FACS, WB, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal HIT2 unconjugated
anti-CD38 antibody (APC)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 APC
anti-CD38 antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal HIT2 PE
anti-CD38 (AA 101-200) antibody适用: 小鼠, 大鼠 FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , IP - Reported in literature , ELISA - Reported in literature , Sep - Reported in literature , Activ - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Apop - Reported in literature , Drug Delivery - Reported in literature , Block - Reported in literature
- Working Dilutions: Flow Cytometry FITC and BIOT conjugates 1 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
- 说明
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Induction of B lymphocyte proliferation
- 样本量
- 1 mL
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
- 储存液
- Without preservative
- 注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C
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- 抗原
- CD38
- Abstract
- CD38 产品
- 背景
- Murine CD38, a type II transmembrane glycoprotein, is a bifunctional ectoenzyme capable of catabolizing nicotinamide adenine dinucleotide (NAD+) to cyclic ADP-ribose (cADPR), and then hydrolyzing cADPR to adenosine diphosphoribose (ADPR). It is expressed at high levels on the surface of peripheral B-lineage cells, and at low density on germinal center B cells from unimmunized mice. It has also been reported to be expressed at moderate levels on NK cells, a proportion of peripheral T cells, and a subpopulation of thymocytes which are mostly TCR+, CD4-, CD8-. Murine CD38 is also expressed by all Mac-1+ macrophages in the peritoneal cavities of unimmunized mice, but not by unstimulated bone-marrow-derived macrophages. Monoclonal antibodies to CD38 have been shown to induce B- and T-cell proliferation, protect B cells from apoptosis, and inhibit B lymphopoiesis.
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