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CD28 抗体

CD28 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 37-51 unconjugated
产品编号 ABIN135184
发货至: 中国
  • 抗原 See all CD28 抗体
    CD28
    适用
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    小鼠
    宿主
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    仓鼠
    克隆类型
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    单克隆
    标记
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    This CD28 antibody is un-conjugated
    应用范围
    • 187
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    Flow Cytometry (FACS)
    特异性
    Mouse CD28, Mr 40 kDa
    产品特性
    Hamster Anti-Mouse CD28-LE/AF
    内毒素水平
    Low endotoxin
    免疫原
    C57BL/6N mouse T cell lymphoma EL-4 cell line
    克隆位点
    37-51
    亚型
    IgG
    Top Product
    Discover our top product CD28 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IP - Reported in literature , Costim - Reported in literature , Stim - Reported in literature , Activ - Reported in literature , Block - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    In vitro costimulation of T cells and NK cells

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of PBS
    储存液
    Azide free
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    -20 °C
    储存方法
    Aliquot and freeze the low endotoxin, azide-free product at -20 °C immediately upon receipt.
  • 抗原
    CD28
    别名
    CD28 (CD28 产品)
    别名
    Tp44 antibody, CD28RNA antibody, cd28 antibody, CD28 molecule antibody, CD28 antigen antibody, Cd28 molecule antibody, CD28 molecule L homeolog antibody, CD28 antibody, Cd28 antibody, cd28.L antibody
    背景
    CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes, and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80/B7-1 and CD86/B7-2 on B cells and other antigen presenting cells, and plays an important role in the interaction between T cells and B cells. CD28 is a co-stimulatory receptor involved in many, but not all, T-cell independent immune responses.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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