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- 抗原 See all Fibrillin (FBL) products
- Fibrillin (FBL)
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适用
- Cow, 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Fibrillin antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC)
- 产品特性
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The antibody detects: Human and bovine fibrillin (Mr 350 kDa), other species not tested
In immunohistochemical staining of paraformaldehyde-fixed human skin, mAb 11C1.3 labels the elastic framework and more specifically the oxytalantic network close to the epidermis. The antibody also exhibits discrete staining of normal fibroblasts in culture and of extracellular (elastin) fibrils in a variety of tissues. There is an aberrant expression of fibrillin in Marfan syndrome. - 免疫原
- Microfibrils from zonular apparatus of bovine eye
- 克隆位点
- 11C1-3
- 亚型
- IgG1
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anti-Fibrillin (FBL) antibody
FBL 适用: Cow, 人 IHC, WB, ICC 宿主: 小鼠 Monoclonal 11C1-3 unconjugated
anti-Fibrillin (FBL) antibody (FITC)FBL 适用: Cow, 人 IHC, ICC 宿主: 小鼠 Monoclonal 11C1-3 FITC
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- 应用备注
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Working Dilution:
Immunohistochemistry: 1:50-1:100 (30-60 min at RT)
Western blotting:1 µg/mL
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. - 样本量
- 1 mL
- 限制
- 仅限研究用
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- 缓冲液
- Product is supplied as 0.2 mg in 1.0 mL of PBS / NaN3.
- 储存液
- Sodium azide
- 注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- 注意事项
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Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. - 储存条件
- 4 °C
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- 抗原
- Fibrillin (FBL)
- 别名
- Fibrillin (FBL 产品)
- 别名
- T24H24.16 antibody, T24H24_16 antibody, fibrillin antibody, fibrillin antibody, hypothetical protein antibody, fibrillar structure forming protein antibody, FIB antibody, T26E3.6 antibody, ORF-18 p10 antibody
- 背景
- The fibrillins are extracellular matrix glycoproteins which occur as a major component of a subset of connective tissue microfibrils. These microfibrils have a beaded appearance and a cross-sectional diameter of 10-12 nm. In elastic tissues, these structures are thought to provide the scaffold onto which elastin is assembled to form elastic fibers, although their function in non-elastic tissues is unclear.
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